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What is the difference between the TDP 1.5, TDP 5 and the TDP 6s?

What is the difference between the TDP 1.5, TDP 5 and the TDP 6s?

This is a frequently asked question on the TDP range. This range of single station pill press includes the TDP 1.5, TDP 5 and TDP 6s. The machines are very similar and the main distinction between them is the pressure that is exerted during tablet making.

Is A Vegetarian Capsule Much Better than One Made of Gelatin

Is A Vegetarian Capsule Much Better than One Made of Gelatin

Medicines are a go to whenever one experiences health problems. From over the counter medicines to prescriptions, these pills have become vital to our everyday lives. Due to the advancement in technology, two different forms are now available – tablets and capsules. For some time, tablets are quite popular way of taking in medication or supplements; later on however, consumers discover the effects of taking tablets.

Cup Depth Demonstrated On Tablet Press Tooling

​Cup and Tablet - Depth and Consistency

The cup depth is the space between the punch tip and the lowest possible measurable area of a cup cavity. In order to form proper inspection and wear limits of the tooling equipment, it is important that one should know about it, and how premature wear can affect the tablet.

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Cool Chain Drugs | What are Cool Chain Drugs?

In the pharmaceutical world, there are certain medicine products that needs certain specific temperature in order to maintain its efficiency, structure and safety.

Coenzyme Q10 concept, 3D rendering isolated on white background

CoQ10 - Why It Should Be Part Of Your Range

Coenzyme Q10, often called CoQ10, is a compound that occurs naturally in the human body. All the cells of the body produce this enzyme, which helps to produce energy for normal cell maintenance and growth.

Different Types Of Contamination, Causes And Prevention For Pharmaceutical Industry

Different Types Of Contamination, Causes And Prevention For Pharmaceutical Industry

The presence of unwanted materials such as dust and particles during the manufacturing and transportation time is called contamination. The term contaminants includes any unwanted matter that is found in the product. These contaminants affect the quality of the product or the process.

Contaminants Caused By Humans And Methods Of Control

Contaminants Caused By Humans And Methods Of Control

One of the major problems with sterile manufacturing is the possibility of contamination. The cleanroom area is one of the hardest places to maintain sterile or clean and is the major source of contamination.

Compression Tooling Equipment

Compression Tooling Equipment

Changing the tablet manufacturing process can lead to better and more improved quality products as well as cost efficiency for the company. By communicating with one’s tooling vendor and taking into consideration the right material type, one can overcome the many problems that tablet companies are facing today.

Common Tablet Problems And Solutions

Common Tablet Problems And Solutions

There are varieties of problems that face the pharmaceutical world, some of which we will be discussing as well as solutions that would help solve these problems.

  • Overwetting of the tablets/Surface pitting. This is where suspension droplets hit the still wet tablet and the drying air does not dry it enough.
  • Physical damages overloading or unloading operation.
  • Poor tablet design – flat surfaces.
  • Spray Drying. The suspension droplets hit the tablet after the moisture has been removed. This leads to the poor adherence of the coat

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Common Tablet Defects That Can Be Avoided Easily

Common Tablet Defects That Can Be Avoided Easily

Tablet defects occur for a variety of reasons, but many can easily be avoided. To address defects, technicians involved in tabletting must have a full understanding of both the tabletting process and the materials used. Adequate training in the setting up and use of the machines is vital if the technician is to have the necessary skills to be able to fix equipment and minimize problems in production.

Common Problems in Tablet Compression

Common Problems in Tablet Compression

In the tablet manufacturing industry, the most common problem that they encounter is what one would call as “Sticking”. This happens when the granulation sticks to the tool face, which results to sticky products and failure of the presses to compress the tablets. This is a big problem for manufacturers as the sticking goes unnoticed and only seen once the item is in production.

Cleaning Agent Used For Pharmaceutical Companies

Cleaning Agent Used For Pharmaceutical Companies

The nonionic detergents are the type of cleaning agent used in the pharmaceutical industry as it helps sanitize and protect the equipment in order to prevent poor quality and thus uphold the quality of the product.

Checking Your Tooling

Checking Your Tooling

It is time consuming and expensive for tablet manufacturers to inspect tooling equipment. That said, changes and advancement in technology makes it easier to doin-processinspections. Below is a brief on the improvement in technology to improvein-processinspection.

Case Studies in Capsule Filling – Improving Performance, Effectiveness and Productivity

Case Studies in Capsule Filling

The rules have changed when it comes to development of products in the pharmaceutical, health and nutritional industry.

Capsule Dosage Forms – Hard Gelatin, Soft Gelatin, Modified Release and Enteric

Capsule Dosage Forms – Hard Gelatin, Soft Gelatin, Modified Release and Enteric

Although LFA Tablet Presses does not sell capsules or capsule fillers we do feel that it is very important to provide our customers with as much information as possible. In this article we discuss the types of capsules and the their potential applications.

Breaker Lines - Good or Bad?

Breaker Lines - Good or Bad?

The use of scoring on tablets has long been implemented by the manufacturing industry mainly to prevent stress fractures but later on for more considerations that are primarily aesthetic. Bisects are different as they present a challenge to manufacturers as they can affect the tablets.

Building strength in to your design

Building strength in to your design

The tablet land is a slight level surface that is vertical to the tablet’s boundary creating a junction between the boundary and the cup of the tablet. There are three main reasons why one would incorporate a land into the tablet’s design.

  1. Increase the strength of the punch edge
  2. Increase the wear of the punch cup inner edges
  3. Lower the relentlessness of the nicks on the edges of the punch
Binder Types and Properties Used in Tablet Manufacturing

Binder Types and Properties Used in Tablet Manufacturing

Binders are chemical compounds that have an adhesive property. They bind the drug and excipient together and provide it with extra strength. Binders can also form intergranular bonds that fuse together and form a binder bridge between granules adhering to each other. The bridges may result from the melting or softening of the binder during the compression process.

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