How to solve Tablet Chipping
Definition: The chipping occurs when the edges of the tablets break during the press process or during the handling and coating.
Reason: May be due to the incorrect equipment setting, misaligned ejection
The Causes And Remedies Of Chipping Related To Formulation (Granulation) Are As Follows
CAUSES | REMEDIES |
---|---|
Sticking on punch faces | Dry the granules properly or increase lubrication. |
Too dry granules. | Moisten the granules to plasticize. Add hygroscopic substances. |
Too much binding causes chipping at bottom. | Optimize binding, or use dry binders. |
The Causes And Remedies Of Chipping Related To Tablet Presses (Dies, Punches And Tablet Press)
CAUSES | REMEDIES |
---|---|
Groove of die worn at compression point. | Polish to open end, reverse or replace the die. |
Barreled die (center of the die wider than ends) | Polish the die to make it cylindrical |
Edge of punch face turned inside/inward. | Polish the punch edges |
Concavity too deep to compress properly. | Reduce concavity of punch faces. Use flat punches. |